diff --git a/src/libslic3r/GCode/ToolOrdering.cpp b/src/libslic3r/GCode/ToolOrdering.cpp
index daa6e9d8a..0a5197132 100644
--- a/src/libslic3r/GCode/ToolOrdering.cpp
+++ b/src/libslic3r/GCode/ToolOrdering.cpp
@@ -842,7 +842,7 @@ void ToolOrdering::reorder_extruders_for_minimum_flush_volume()
     const unsigned int number_of_extruders = (unsigned int) (sqrt(flush_matrix.size()) + EPSILON);
     // Extract purging volumes for each extruder pair:
     std::vector<std::vector<float>> wipe_volumes;
-    if (print_config->purge_in_prime_tower || m_is_BBL_printer) {
+    if ((print_config->purge_in_prime_tower && print_config->single_extruder_multi_material) || m_is_BBL_printer) {
         for (unsigned int i = 0; i < number_of_extruders; ++i)
             wipe_volumes.push_back( std::vector<float>(flush_matrix.begin() + i * number_of_extruders,
                                                        flush_matrix.begin() + (i + 1) * number_of_extruders));
diff --git a/src/libslic3r/Print.cpp b/src/libslic3r/Print.cpp
index b3a9db6f3..058a48514 100644
--- a/src/libslic3r/Print.cpp
+++ b/src/libslic3r/Print.cpp
@@ -2596,7 +2596,7 @@ const WipeTowerData &Print::wipe_tower_data(size_t filaments_cnt) const
     if (!is_step_done(psWipeTower) && filaments_cnt != 0) {
         double width        = m_config.prime_tower_width;
         double layer_height = 0.2; // hard code layer height
-        if (m_config.purge_in_prime_tower) {
+        if (m_config.purge_in_prime_tower && m_config.single_extruder_multi_material) {
             // Calculating depth should take into account currently set wiping volumes.
             // For a long time, the initial preview would just use 900/width per toolchange (15mm on a 60mm wide tower)
             // and it worked well enough. Let's try to do slightly better by accounting for the purging volumes.
@@ -2645,7 +2645,7 @@ void Print::_make_wipe_tower()
 
     const auto bUseWipeTower2 = is_BBL_printer() ? false : true;
     // Orca: itertate over wipe_volumes and change the non-zero values to the prime_volume
-    if (!m_config.purge_in_prime_tower && !is_BBL_printer()) {
+    if ((!m_config.purge_in_prime_tower || !m_config.single_extruder_multi_material) && !is_BBL_printer()) {
         for (unsigned int i = 0; i < number_of_extruders; ++i) {
             for (unsigned int j = 0; j < number_of_extruders; ++j) {
                 if (wipe_volumes[i][j] > 0) {
@@ -2824,7 +2824,7 @@ void Print::_make_wipe_tower()
                     if ((first_layer && extruder_id == m_wipe_tower_data.tool_ordering.all_extruders().back()) || extruder_id !=
                         current_extruder_id) {
                         float volume_to_wipe = m_config.prime_volume;
-                        if (m_config.purge_in_prime_tower) {
+                        if (m_config.purge_in_prime_tower && m_config.single_extruder_multi_material) {
                             volume_to_wipe = wipe_volumes[current_extruder_id][extruder_id]; // total volume to wipe after this toolchange
                             volume_to_wipe *= m_config.flush_multiplier;
                             // Not all of that can be used for infill purging:
diff --git a/src/slic3r/GUI/Tab.cpp b/src/slic3r/GUI/Tab.cpp
index b95ace823..13805084b 100644
--- a/src/slic3r/GUI/Tab.cpp
+++ b/src/slic3r/GUI/Tab.cpp
@@ -1665,6 +1665,13 @@ void Tab::on_value_change(const std::string& opt_key, const boost::any& value)
         wxGetApp().preset_bundle->export_selections(*wxGetApp().app_config);
     }
 
+    //Orca: disable purge_in_prime_tower if single_extruder_multi_material is disabled
+    if (opt_key == "single_extruder_multi_material" && m_config->opt_bool("single_extruder_multi_material") == false){
+        DynamicPrintConfig new_conf = *m_config;
+        new_conf.set_key_value("purge_in_prime_tower", new ConfigOptionBool(false));
+        m_config_manipulation.apply(m_config, &new_conf);
+    }
+
     if (m_postpone_update_ui) {
         // It means that not all values are rolled to the system/last saved values jet.
         // And call of the update() can causes a redundant check of the config values,